Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression.

GCN4 is a transcriptional activator of amino acid-biosynthetic genes in the yeast Saccharomyces cerevisiae. GCN2, a translational activator of GCN4 expression, contains a domain homologous to the catalytic subunit of eucaryotic protein kinases. Substitution of a highly conserved lysine residue in th...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Wek, R C, Ramirez, M, Jackson, B M, Hinnebusch, A G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2188100/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.6.2820-2831.1990
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