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Redox-Sensitive Up-Regulation of eNOS by Purple Grape Juice in Endothelial Cells: Role of PI3-Kinase/Akt, p38 MAPK, JNK, FoxO1 and FoxO3a

The vascular protective effect of grape-derived polyphenols has been attributable, in part, to their direct action on blood vessels by stimulating the endothelial formation of nitric oxide (NO). The aim of the present study was to determine whether Concord grape juice (CGJ), which contains high leve...

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Autors principals: Alhosin, Mahmoud, Anselm, Eric, Rashid, Sherzad, Kim, Jong Hun, Frota Madeira, Socorro Vanesca, Bronner, Christian, Schini-Kerth, Valérie B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606366/
https://ncbi.nlm.nih.gov/pubmed/23533577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057883
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