Differential Denaturation of Serum Proteome Reveals a Significant Amount of Hidden Information in Complex Mixtures of Proteins

Recently developed proteomic technologies allow to profile thousands of proteins within a high-throughput approach towards biomarker discovery, although results are not as satisfactory as expected. In the present study we demonstrate that serum proteome denaturation is a key underestimated feature;...

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Détails bibliographiques
Auteurs principaux: Verdoliva, Vincenzo, Senatore, Cinzia, Polci, Maria Letizia, Rossi, Stefania, Cordella, Martina, Carlucci, Giuseppe, Marchetti, Paolo, Antonini-Cappellini, Giancarlo, Facchiano, Antonio, D'Arcangelo, Daniela, Facchiano, Francesco
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606341/
https://ncbi.nlm.nih.gov/pubmed/23533572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057104
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