Identification and characterization of two distinct PPP1R2 isoforms in human spermatozoa

BACKGROUND: Protein Ser/Thr Phosphatase PPP1CC2 is an alternatively spliced isoform of PPP1C that is highly enriched in testis and selectively expressed in sperm. Addition of the phosphatase inhibitor toxins okadaic acid or calyculin A to caput and caudal sperm triggers and stimulates motility, resp...

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Auteurs principaux: Korrodi-Gregório, Luis, Ferreira, Mónica, Vintém, Ana Paula, Wu, Wenjuan, Muller, Thorsten, Marcus, Katrin, Vijayaraghavan, Srinivasan, Brautigan, David L, da Cruz e Silva, Odete A B, Fardilha, Margarida, da Cruz e Silva, Edgar F
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606321/
https://ncbi.nlm.nih.gov/pubmed/23506001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-14-15
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