Targeted Ablation of miR-21 Decreases Murine Eosinophil Progenitor Cell Growth

MiR-21 is one of the most up-regulated miRNAs in multiple allergic diseases associated with eosinophilia and has been shown to positively correlate with eosinophil levels. Herein, we show that miR-21 is up-regulated during IL-5-driven eosinophil differentiation from progenitor cells in vitro. Target...

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Main Authors: Lu, Thomas X., Lim, Eun-Jin, Itskovich, Svetlana, Besse, John A., Plassard, Andrew J., Mingler, Melissa K., Rothenberg, Joelle A., Fulkerson, Patricia C., Aronow, Bruce J., Rothenberg, Marc E.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606295/
https://ncbi.nlm.nih.gov/pubmed/23533623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059397
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