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The heterochronic microRNA let-7 inhibits cell motility by regulating the genes in the actin cytoskeleton pathway in breast cancer

The heterochronic gene let-7 serves as a tumor suppressor microRNA by targeting various oncogenic pathways in cancer cells. Considerable evidence indicates that reduced expression of let-7 might be associated with poor clinical outcome in patients with cancer. Here, we report that the expression lev...

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Bibliographische Detailangaben
Hauptverfasser: Hu, Xiaowen, Guo, Jinyi, Zheng, Lan, Li, Chunsheng, Zheng, Tim M., Tanyi, Janos L., Liang, Shun, Benedetto, Chiara, Mitidieri, Marco, Katsaros, Dionyssios, Zhao, Xia, Zhang, Youcheng, Huang, Qihong, Zhang, Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606291/
https://ncbi.nlm.nih.gov/pubmed/23339187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0432
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