The Drosophila melanogaster CHD1 Chromatin Remodeling Factor Modulates Global Chromosome Structure and Counteracts HP1a and H3K9me2

CHD1 is a conserved chromatin remodeling factor that localizes to active genes and functions in nucleosome assembly and positioning as well as histone turnover. Mouse CHD1 is required for the maintenance of stem cell pluripotency while human CHD1 may function as a tumor suppressor. To investigate th...

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Bibliographic Details
Main Authors: Bugga, Lakshmi, McDaniel, Ivy E., Engie, Liana, Armstrong, Jennifer A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606111/
https://ncbi.nlm.nih.gov/pubmed/23533627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059496
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