Pharmacological inhibition of VIP signaling enhances antiviral immunity and improves survival in murine cytomegalovirus-infected allogeneic bone marrow transplant recipients

Cytomegalovirus (CMV) infection following allogeneic bone marrow transplant (allo-BMT) is controlled by donor-derived cellular immunity. Vasoactive intestinal peptide (VIP) suppresses Th1 immunity. We hypothesized that blocking VIP-signaling would enhance anti-CMV immunity in murine recipients of al...

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Библиографические подробности
Главные авторы: Li, Jian-Ming, Hossain, Mohammad S., Southerland, Lauren, Waller, Edmund K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2013
Предметы:
Transplantation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606069/
https://ncbi.nlm.nih.gov/pubmed/23325838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-437640
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