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Structural studies of Pseudomonas and Chromobacterium ω-aminotransferases provide insights into their differing substrate specificity

The crystal structures and inhibitor complexes of two industrially important ω-aminotransferase enzymes from Pseudomonas aeruginosa and Chromobacterium violaceum have been determined in order to understand the differences in their substrate specificity. The two enzymes share 30% sequence identity an...

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Detalhes bibliográficos
Main Authors: Sayer, Christopher, Isupov, Michail N., Westlake, Aaron, Littlechild, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606037/
https://ncbi.nlm.nih.gov/pubmed/23519665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444912051670
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