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Activated CD4+ T Cells Target Mesangial Antigens and Initiate Glomerulonephritis

AIMS: The role of kidney infiltrating T cells in the pathology of lupus nephritis is unclear. This study was undertaken to investigate whether CD4+ T cell responses to a surrogate mesangial antigen can initiate glomerulonephritis. METHODS: Ovalbumin was deposited in the glomerular mesangium of C57BL...

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Библиографические подробности
Главные авторы: Scindia, Yogesh, Nackiewicz, Dominika, Dey, Paromita, Szymula, Agneiszka, Bajwa, Amandeep, Rosin, Diane, Bolton, W. Kline, Okusa, Mark, Deshmukh, Umesh, Bagavant, Harini
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606022/
https://ncbi.nlm.nih.gov/pubmed/23095207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000342368
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