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Sirtuin Activation: A Role for Plasma Membrane in the Cell Growth Puzzle

For more than 20 years, the observation that impermeable oxidants can stimulate cell growth has not been satisfactorily explained. The discovery of sirtuins provides a logical answer to the puzzle. The NADH-dependent transplasma membrane electron transport system, which is stimulated by growth facto...

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Autors principals: Crane, Frederick L., Navas, Plácido, Low, Hans, Sun, Iris L., de Cabo, Rafael
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605909/
https://ncbi.nlm.nih.gov/pubmed/23033342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gls184
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