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Transcriptional Analysis of Histone Deacetylase Family Members Reveal Similarities Between Differentiating and Aging Spermatogonial Stem Cells

The differentiation of adult stem cells involves extensive chromatin remodeling, mediated in part by the gene products of histone deacetylase (HDAC) family members. While the transcriptional downregulation of HDACs can impede stem cell self-renewal in certain contexts, it may also promote stem cell...

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Detalhes bibliográficos
Main Authors: Kofman, Amber E., Huszar, Jessica M., Payne, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605728/
https://ncbi.nlm.nih.gov/pubmed/22729928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-012-9392-5
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