Association of ABCC10 polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS

BACKGROUND: Nevirapine exhibits marked interpatient variability in pharmacokinetics. CYP2B6 activity and demographic factors are important, but there are a few data on drug transporters for nevirapine. ABCC10 (MRP7) is an efflux transporter highly expressed in liver, intestine, and peripheral blood...

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Autors principals: Liptrott, Neill J., Pushpakom, Sudeep, Wyen, Christoph, Fätkenheuer, Gerd, Hoffmann, Christian, Mauss, Stefan, Knechten, Heribert, Brockmeyer, Norbert H., Hopper-Borge, Elizabeth, Siccardi, Marco, Back, David J., Khoo, Saye H., Pirmohamed, Munir, Owen, Andrew
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605700/
https://ncbi.nlm.nih.gov/pubmed/22082652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32834dd82e
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