Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha).

Retinoic acid (RA) induces terminal granulocytic differentiation of the HL-60 promyelocytic leukemia cell line as well as certain other human myeloid leukemias. Specific RA receptors that are members of the steroid-thyroid hormone superfamily of nuclear transcription factors have recently been ident...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Collins, S J, Robertson, K A, Mueller, L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360563/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1970118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.5.2154-2163.1990
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