The effect of microgrooved culture substrates on calcium cycling of cardiac myocytes derived from human induced pluripotent stem cells

Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) have been widely proposed as in vitro models of myocardial physiology and disease. A significant obstacle, however, is their immature phenotype. We hypothesised that Ca(2+) cycling of iPSC-CM is influenced by culture conditions and can b...

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Detalhes bibliográficos
Main Authors: Rao, Christopher, Prodromakis, Themistoklis, Kolker, Ljudmila, Chaudhry, Umar A.R., Trantidou, Tatiana, Sridhar, Arun, Weekes, Claire, Camelliti, Patrizia, Harding, Sian E., Darzi, Ara, Yacoub, Magdi H., Athanasiou, Thanos, Terracciano, Cesare M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605579/
https://ncbi.nlm.nih.gov/pubmed/23261219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.11.055
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