Direct and Specific Effect of Sevoflurane Anesthesia on rat Per2 Expression in the Suprachiasmatic Nucleus

BACKGROUND: Our previous studies revealed that application of the inhalation anesthetic, sevoflurane, reversibly repressed the expression of Per2 in the mouse suprachiasmatic nucleus (SCN). We aimed to examine whether sevoflurane directly affects the SCN. METHODS: We performed in vivo and in vitro e...

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Detalhes bibliográficos
Main Authors: Anzai, Megumi, Iijima, Norio, Higo, Shimpei, Takumi, Ken, Matsuo, Izumi, Mori, Keisuke, Ohe, Yumiko, Kadota, Kana, Akimoto, Toshio, Sakamoto, Atsuhiro, Ozawa, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605447/
https://ncbi.nlm.nih.gov/pubmed/23555676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059454
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