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Cleavage of a hydrophilic C-terminal domain increases growth-inhibitory activity of oncostatin M.

Oncostatin M is a polypeptide cytokine, produced by normal and malignant hematopoietic cells, that has several in vitro activities, including the ability to inhibit growth of cultured carcinoma cells. Here we present a structural and functional comparison of two oncostatin M-related proteins (Mr 36,...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Linsley, P S, Kallestad, J, Ochs, V, Neubauer, M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2325640/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.5.1882-1890.1990
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