Intragastric exposure to titanium dioxide nanoparticles induced nephrotoxicity in mice, assessed by physiological and gene expression modifications

BACKGROUND: Numerous studies have demonstrated that titanium dioxide nanoparticles (TiO(2) NPs) induced nephrotoxicity in animals. However, the nephrotoxic multiple molecular mechanisms are not clearly understood. METHODS: Mice were exposed to 2.5, 5 and 10 mg/kg TiO(2) NPs by intragastric administr...

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Autori principali: Gui, Suxin, Sang, Xuezi, Zheng, Lei, Ze, Yuguan, Zhao, Xiaoyang, Sheng, Lei, Sun, Qingqing, Cheng, Zhe, Cheng, Jie, Hu, Renping, Wang, Ling, Hong, Fashui, Tang, Meng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605279/
https://ncbi.nlm.nih.gov/pubmed/23406204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-10-4
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