Anesthetics Interfere with Axon Guidance in Developing Mouse Neocortical Neurons In Vitro via a γ-Aminobutyric Acid Type A Receptor Mechanism

BACKGROUND: The finding that exposure to general anesthetics (GAs) in childhood may increase rates of learning disabilities has raised a concern that anesthetics may interfere with brain development. The generation of neuronal circuits, a complex process in which axons follow guidance cues to dendri...

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Autori principali: Mintz, C. David, Barrett, Kendall M.S., Smith, Sarah C., Benson, Deanna L., Harrison, Neil L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605271/
https://ncbi.nlm.nih.gov/pubmed/23364597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318287b850
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