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A mutation in the tRNA nucleotidyltransferase gene promotes stabilization of mRNAs in Saccharomyces cerevisiae.

To identify trans-acting factors involved in mRNA decay in the yeast Saccharomyces cerevisiae, we have begun to characterize conditional lethal mutants that affect mRNA steady-state levels. A screen of a collection of temperature-sensitive mutants identified ts352, a mutant that accumulated moderate...

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Pubblicato in:Mol Cell Biol
Autori principali: Peltz, S W, Donahue, J L, Jacobson, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1448105/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.12.5778-5784.1992
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