Truncated protein phosphatase GLC7 restores translational activation of GCN4 expression in yeast mutants defective for the eIF-2 alpha kinase GCN2.

GCN2 is a protein kinase in Saccharomyces cerevisiae that is required for increased expression of the transcriptional activator GCN4 in amino acid-starved cells. GCN2 stimulates GCN4 synthesis at the translational level by phosphorylating the alpha subunit of eukaryotic translation initiation factor...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Wek, R C, Cannon, J F, Dever, T E, Hinnebusch, A G
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1992
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360510/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1333044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.12.5700
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