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Bayesian Estimation of Mixture Models with Prespecified Elements to Compare Drug Resistance in Treatment-Naïve and Experienced Tuberculosis Cases

We propose a Bayesian approach for estimating branching tree mixture models to compare drug-resistance pathways (i.e. patterns of sequential acquisition of resistance to individual antibiotics) that are observed among Mycobacterium tuberculosis isolates collected from treatment-naïve and treatment-e...

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Bibliografiske detaljer
Main Authors: Izu, Alane, Cohen, Ted, DeGruttola, Victor
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605089/
https://ncbi.nlm.nih.gov/pubmed/23555210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002973
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