Structural basis for the inhibition of Mycobacterium tuberculosis l,d-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains

Difficulty in the treatment of tuberculosis and growing drug resistance in Mycobacterium tuberculosis (Mtb) are a global health issue. Carbapenems inactivate l,d-transpeptidases; meropenem, when administered with clavulanate, showed in vivo activity against extensively drug-resistant Mtb strains. Ld...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kim, Hyoun Sook, Kim, Jieun, Im, Ha Na, Yoon, Ji Young, An, Doo Ri, Yoon, Hye Jin, Kim, Jin Young, Min, Hye Kyeoung, Kim, Soon-Jong, Lee, Jae Young, Han, Byung Woo, Suh, Se Won
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605043/
https://ncbi.nlm.nih.gov/pubmed/23519417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444912048998
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados