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Mössbauer Properties of the Diferric Cluster and the Differential Iron(II)-Binding Affinity of the Iron Sites in Protein R2 of Class Ia Escherichia coli Ribonucleotide Reductase: A DFT/Electrostatics Study

The R2 subunit of class-Ia ribonucleotide reductase (RNR) from Escherichia coli (E. coli) contains a diiron active site. Starting from the apo-protein and Fe(II) in solution at low Fe(II)/apoR2 ratios, mononuclear Fe(II) binding is observed indicating possible different Fe(II) binding affinities for...

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Detalhes bibliográficos
Main Authors: Han, Wen-Ge, Sandala, Gregory M., Giammona, Debra Ann, Bashford, Donald, Noodleman, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604995/
https://ncbi.nlm.nih.gov/pubmed/21837345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1dt10950b
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