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A preclinical rodent model of radiation induced lung injury for medical countermeasure screening in accordance with the FDA animal rule

The purpose of pre-clinical murine model development is to establish that the pathophysiological outcome of our rodent model of radiation-induced lung injury is sufficiently representative of the anticipated pulmonary response in the human population. This objective is based on concerns that the C57...

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Detalhes bibliográficos
Main Authors: Jackson, Isabel L., Xu, Puting, Hadley, Caroline, Katz, Barry P., McGurk, Ross, Down, Julian D., Vujaskovic, Zeljko
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604892/
https://ncbi.nlm.nih.gov/pubmed/22929472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HP.0b013e31826386ef
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