I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection

Dendritic cells (DC) are required for priming antigen-specific T cells and acquired immunity to many important human pathogens, including Mycobacteriuim tuberculosis (TB) and influenza. However, inappropriate priming of auto-reactive T cells is linked with autoimmune disease. Understanding the molec...

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Bibliografiske detaljer
Main Authors: Mancino, Alessandra, Habbeddine, Mohamed, Johnson, Ella, Luron, Lionel, Bebien, Magali, Memet, Sylvie, Fong, Carol, Bajenoff, Marc, Wu, Xuefeng, Karin, Michael, Caamano, Jorge, Chi, Hongbo, Seed, Michael, Lawrence, Toby
Format: Artigo
Sprog:Inglês
Udgivet: European Molecular Biology Organization 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604721/
https://ncbi.nlm.nih.gov/pubmed/23422957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.28
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