The growth-stimulatory effect of simian virus 40 T antigen requires the interaction of insulinlike growth factor 1 with its receptor.

We have used a plasmid expressing a temperature-sensitive (ts) mutant of simian virus 40 (SV40) T antigen, stably transfected into 3T3 cells, to study the role of insulinlike growth factor 1 (IGF-1) and its receptor in T-antigen-mediated growth. While 3T3 cells do not grow in serum-free medium, in 1...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Porcu, P, Ferber, A, Pietrzkowski, Z, Roberts, C T, Adamo, M, LeRoith, D, Baserga, R
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360440/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1406682/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.11.5069
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