Silymarin inhibits ultraviolet radiation-induced immune suppression through DNA repair-dependent activation of dendritic cells and stimulation of effector T cells

Silymarin inhibits UVB-induced immunosuppression in mouse skin. To identify the molecular mechanisms underlying this effect, we used an adoptive transfer approach in which dendritic cells (DCs) from the draining lymph nodes of donor mice that had been UVB-exposed and sensitized to 2,4,-dinitrofluoro...

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Bibliografiske detaljer
Main Authors: Vaid, Mudit, Prasad, Ram, Singh, Tripti, Elmets, Craig A., Xu, Hui, Katiyar, Santosh K.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604166/
https://ncbi.nlm.nih.gov/pubmed/23395695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.01.026
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