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A mammalian factor that binds telomeric TTAGGG repeats in vitro.

We have identified a DNA-binding activity with specificity for the TTAGGG repeat arrays found at mammalian telomeres. This factor, called TTAGGG repeat factor (TRF), is present in nuclear extracts of human, mouse, and monkey cells. TRF from HeLa cells was characterized in detail by electrophoretic m...

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Publicat a:Mol Cell Biol
Autors principals: Zhong, Z, Shiue, L, Kaplan, S, de Lange, T
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360416/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1406665/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.11.4834-4843.1992
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