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Allogeneic Bone Marrow Co-Cultured with Human Islets Significantly Improves Islet Survival and Function in vivo

BACKGROUND: A significant barrier to islet transplantation is the rapid loss of human islet function in vivo. The present study evaluates whether bone marrow (BM) could be used to support human islet survival and function in vivo. METHODS: We co-cultured human islets and BM for three weeks prior to...

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Autori principali: Luo, John ZQ, Xiong, Fang, Al-Homsi, A Samer, Ricordi, Camillo, Luo, LuGuang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604119/
https://ncbi.nlm.nih.gov/pubmed/23416682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31828235c7
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