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Protein Kinase C–ζ Mediates Lung Injury Induced by Diesel Exhaust Particles

Recently, we reported that diesel exhaust particles (DEPs) disrupt tight junctions (TJs) in alveolar epithelial cells (AECs) via an increase in reactive oxygen species (ROS). In this study, we investigated the role of protein kinase C (PKC)–ζ activation in DEP-induced lung injury. C57/bl6 mice were...

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Bibliografiske detaljer
Main Authors: Caraballo, Juan C., Borcherding, Jennifer, Thorne, Peter S., Comellas, Alejandro P.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604088/
https://ncbi.nlm.nih.gov/pubmed/23221045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0056OC
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