Chemerin Is an Antimicrobial Agent in Human Epidermis

Chemerin, a chemoattractant ligand for chemokine-like receptor 1 (CMKLR1) is predicted to share similar tertiary structure with antibacterial cathelicidins. Recombinant chemerin has antimicrobial activity. Here we show that endogenous chemerin is abundant in human epidermis, and that inhibition of b...

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Detalhes bibliográficos
Main Authors: Banas, Magdalena, Zabieglo, Katarzyna, Kasetty, Gopinath, Kapinska-Mrowiecka, Monika, Borowczyk, Julia, Drukala, Justyna, Murzyn, Krzysztof, Zabel, Brian A., Butcher, Eugene C., Schroeder, Jens M., Schmidtchen, Artur, Cichy, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604073/
https://ncbi.nlm.nih.gov/pubmed/23527010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058709
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