Activated lck tyrosine protein kinase stimulates antigen-independent interleukin-2 production in T cells.
p56lck, a member of the src family of cytoplasmic tyrosine kinases, is expressed predominantly in T cells where it associates with the T-cell surface molecules CD4 and CD8. Mutants of CD4 and CD8 that have lost the ability to associate with p56lck no longer enhance antigen-induced T-cell activation....
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1992
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360399/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1383689/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.10.4724-4732.1992 |
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