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Pharmacological Inhibition of Glycogen Synthase Kinase 3 Regulates T Cell Development In Vitro
The development of functional T cells requires receptor-mediated transition through multiple checkpoints in the thymus. Double negative 3 (DN3) thymocytes are selected for the presence of a rearranged TCR beta chain in a process termed β-selection which requires signalling via the pre-TCR, Notch1 an...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3603984/ https://ncbi.nlm.nih.gov/pubmed/23526989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058501 |
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