The IKK Inhibitor Bay 11-7082 Induces Cell Death Independent from Inhibition of Activation of NFκB Transcription Factors

Multiple myeloma (MM) displays an NFκB activity-related gene expression signature and about 20% of primary MM samples harbor genetic alterations conducive to intrinsic NFκB signaling activation. The relevance of blocking the classical versus the alternative NFκB signaling pathway and the molecular e...

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Détails bibliographiques
Auteurs principaux: Rauert-Wunderlich, Hilka, Siegmund, Daniela, Maier, Eduard, Giner, Tina, Bargou, Ralf C., Wajant, Harald, Stühmer, Thorsten
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603909/
https://ncbi.nlm.nih.gov/pubmed/23527154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059292
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