Cyclic AMP-dependent protein kinase inhibits the activity of myogenic helix-loop-helix proteins.

Differentiation of skeletal muscle cells is inhibited by the cyclic AMP (cAMP) signal transduction pathway. Here we report that the catalytic subunit of cAMP-dependent protein kinase (PKA) can substitute for cAMP and suppress muscle-specific transcription by silencing the activity of the MyoD family...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, L, Heller-Harrison, R, Czech, M, Olson, E N
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC360373/
https://ncbi.nlm.nih.gov/pubmed/1328856
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