DNA Damage Sensor γ-H2AX Is Increased in Preneoplastic Lesions of Hepatocellular Carcinoma

Background. Phosphorylated histone H2AX (γ-H2AX) is a potential regulator of DNA repair and is a useful tool for detecting DNA damage. To evaluate the clinical usefulness of γ-H2AX in hepatocellular carcinoma (HCC), we measured the level of γ-H2AX in HCC, dysplastic nodule, and nontumorous liver dis...

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Detalhes bibliográficos
Main Authors: Matsuda, Yasunobu, Wakai, Toshifumi, Kubota, Masayuki, Osawa, Mami, Takamura, Masaaki, Yamagiwa, Satoshi, Aoyagi, Yutaka, Sanpei, Ayumi, Fujimaki, Shun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603670/
https://ncbi.nlm.nih.gov/pubmed/23533353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/597095
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