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Identification of a 60-kilodalton Rb-binding protein, RBP60, that allows the Rb-E2F complex to bind DNA.

Several reports have indicated that the product of the retinoblastoma gene (Rb) complexes with the transcription factor E2F. We present evidence that the DNA-binding of the Rb-E2F complex involves another cellular factor. Addition of Rb to purified preparations of E2F does not generate an Rb-E2F com...

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Udgivet i:Mol Cell Biol
Principais autores: Ray, S K, Arroyo, M, Bagchi, S, Raychaudhuri, P
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360356/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1406625/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.10.4327-4333.1992
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