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RPC53 encodes a subunit of Saccharomyces cerevisiae RNA polymerase C (III) whose inactivation leads to a predominantly G1 arrest.

RPC53 is shown to be an essential gene encoding the C53 subunit specifically associated with yeast RNA polymerase C (III). Temperature-sensitive rpc53 mutants were generated and showed a rapid inhibition of tRNA synthesis after transfer to the restrictive temperature. Unexpectedly, the rpc53 mutants...

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Udgivet i:Mol Cell Biol
Principais autores: Mann, C, Micouin, J Y, Chiannilkulchai, N, Treich, I, Buhler, J M, Sentenac, A
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360355/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1406624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.10.4314-4326.1992
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