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Lysosomes shape Ins(1,4,5)P(3)-evoked Ca(2+) signals by selectively sequestering Ca(2+) released from the endoplasmic reticulum

Most intracellular Ca(2+) signals result from opening of Ca(2+) channels in the plasma membrane or endoplasmic reticulum (ER), and they are reversed by active transport across these membranes or by shuttling Ca(2+) into mitochondria. Ca(2+) channels in lysosomes contribute to endo-lysosomal traffick...

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Detalhes bibliográficos
Main Authors: López-Sanjurjo, Cristina I., Tovey, Stephen C., Prole, David L., Taylor, Colin W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603520/
https://ncbi.nlm.nih.gov/pubmed/23097044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.116103
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