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Regulated expression of a mammalian nonsense suppressor tRNA gene in vivo and in vitro using the lac operator/repressor system.

We have exploited the Escherichia coli lac operator/repressor system as a means to regulate the expression of a mammalian tRNA gene in vivo and in vitro. An oligonucleotide containing a lac operator (lacO) site was cloned immediately upstream of a human serine amber suppressor (Su+) tRNA gene. Inser...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Syroid, D E, Tapping, R I, Capone, J P
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360350/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1406620/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.10.4271
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