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Fluorescent Phosphatidylinositol 4,5-Bisphosphate Derivatives with Modified 6-Hydroxy Group as Novel Substrates for Phospholipase C

The capacity to monitor spatiotemporal activity of phospholipase C (PLC) isozymes with a PLC-selective sensor would dramatically enhance understanding of the physiological function and disease relevance of these signaling proteins. Previous structural and biochemical studies defined critical roles f...

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書誌詳細
主要な著者: Wang, Xiaoyang, Barrett, Matthew, Sondek, John, Harden, T. Kendall, Zhang, Qisheng
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603374/
https://ncbi.nlm.nih.gov/pubmed/22703043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300637h
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