Effect of PSI‐697, a Novel P‐Selectin Inhibitor, on Platelet–Monocyte Aggregate Formation in Humans

BACKGROUND: Platelet activation is central to the pathogenesis of acute coronary syndromes. Surface expression of P‐selectin on activated platelets induces formation of platelet–monocyte aggregates and promotes vascular inflammation and thrombosis. P‐selectin antagonism may represent a novel therape...

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Detalhes bibliográficos
Main Authors: Japp, Alan G., Chelliah, Raj, Tattersall, Laura, Lang, Ninian N., Meng, Xu, Weisel, Kathleen, Katz, Arie, Burt, David, Fox, Keith A. A., Feuerstein, Giora Z., Connolly, Thomas M., Newby, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603266/
https://ncbi.nlm.nih.gov/pubmed/23525448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.006007
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