Kaposi Sarcoma–Associated Herpesvirus G Protein–Coupled Receptor Enhances Endothelial Cell Survival in Part by Upregulation of Bcl-2

BACKGROUND: Kaposi sarcoma–associated herpesvirus (KSHV) encoded G protein–coupled receptor (vGPCR) is a constitutively active lytic phase protein with significant homology to the human interleukin-8 receptor. vGPCR is necessary and sufficient to induce angiogenesis as well as the spindle cell proli...

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Detalhes bibliográficos
Main Authors: Abboud, Elizabeth R., Shelby, Bryan D., Angelova, Magdalena, Nelson, Anne B., Ferris, MaryBeth, McFerrin, Harris E., Morris, Cindy A., Sullivan, Deborah E.
Formato: Artigo
Idioma:Inglês
Publicado em: the Academic Division of Ochsner Clinic Foundation 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603191/
https://ncbi.nlm.nih.gov/pubmed/23532945
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