A Cell-Impermeable Cyclosporine A Derivative Reduces Pathology in a Mouse Model of Allergic Lung Inflammation

Although the main regulators of leukocyte trafficking are chemokines, another family of chemotactic agents is cyclophilins. Intracellular cyclophilins function as peptidyl-protyl cis-trans isomerases and are targets of the immunosuppressive drug, cyclosporine A (CsA). Cyclophilins can also be secret...

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Bibliografiske detaljer
Main Authors: Balsley, Molly A., Malesevic, Miroslav, Stemmy, Erik J., Gigley, Jason, Jurjus, Rosalyn A., Herzog, Dallen, Bukrinsky, Michael I., Fischer, Gunter, Constant, Stephanie L.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603141/
https://ncbi.nlm.nih.gov/pubmed/21057089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001707
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