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QUANTITATIVE PHOSPHOPROTEOMIC ANALYSIS OF T CELL RECEPTOR SIGNALING IN DIABETES PRONE AND RESISTANT MICE

Type 1 diabetes, in human patients and NOD mice, results from immune attack on insulin-producing beta-cells of the pancreas by autoreactive T lymphocytes. In NOD mice, genetically-controlled perturbations in the signaling pathways downstream of the antigen-specific T cell receptor (TCR) may be instr...

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Bibliografski detalji
Glavni autori: Iwai, Leo K., Benoist, Christophe, Mathis, Diane, White, Forest M
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603002/
https://ncbi.nlm.nih.gov/pubmed/20438120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr100035b
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