NFAT Binding and Regulation of T Cell Activation by the Cytoplasmic Scaffolding Homer Proteins

T cell receptor (TCR) and costimulatory receptor (CD28) signals cooperate in activating T cells, although understanding of how these pathways are themselves regulated is incomplete. We found that Homer2 and Homer3, members of the Homer family of cytoplasmic scaffolding proteins, are negative regulat...

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Detalhes bibliográficos
Main Authors: Huang, Guo N., Huso, David L., Bouyain, Samuel, Tu, Jianchen, McCorkell, Kelly A., May, Michael J., Zhu, Yuwen, Lutz, Michael, Collins, Samuel, Dehoff, Marlin, Kang, Shin, Whartenby, Katharine, Powell, Jonathan, Leahy, Daniel, Worley, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602998/
https://ncbi.nlm.nih.gov/pubmed/18218901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1151227
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