Exploration of gene-environment interactions, maternal effects, and parent-of-origin effects in the etiology of hypospadias

PURPOSE: Hypospadias is a common congenital malformation of the male external genitalia. Association studies for single nucleotide polymorphisms (SNPs) in genes encoding steroid-5-alpha-reductase (SRD5A2), estrogen receptors 1 (ESR1) and 2 (ESR2), and activating transcription factor 3 (ATF3) have be...

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Main Authors: van der Zanden, Loes F.M., Galesloot, Tessel E., Feitz, Wout F.J., Brouwers, Marijn M., Shi, Min, Knoers, Nine V.A.M., Franke, Barbara, Roeleveld, Nel, van Rooij, Iris A.L.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602843/
https://ncbi.nlm.nih.gov/pubmed/23088992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2012.08.033
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