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Differentiation arrest and stromal cell-independent growth of murine erythroleukemia cells are associated with elevated expression of ets-related genes but not with mutation of p53.

The ELM erythroleukemia is novel in that long-term survival of leukemic cells in culture (ELM-D cells) is dependent on contact with a bone marrow-derived stromal feeder cell layer. However, a number of stroma-independent (ELM-I) mutants that vary in their ability to differentiate in vitro in respons...

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Main Authors: Nibbs, R J, Itoh, K, Ostertag, W, Harrison, P R
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC360280/
https://ncbi.nlm.nih.gov/pubmed/8355701
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