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Transforming growth factor-β(1) receptor inhibition preserves glomerulotubular integrity during ureteral obstruction in adults but worsens injury in neonatal mice
Unilateral ureteral obstruction (UUO), a widely used model of chronic kidney disease and congenital obstructive uropathy, causes proximal tubular injury and formation of atubular glomeruli. Because transforming growth factor-β(1) (TGF-β(1)) is a central regulator of renal injury, neonatal and adult...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Physiological Society
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3602709/ https://ncbi.nlm.nih.gov/pubmed/23303407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00496.2012 |
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